Antithrombotic Therapies in COVID-19 Disease: a Systematic Review.

ABSTRACT:

Background

Infection with coronavirus SARS-CoV-2, causing COVID-19 disease, leads to inflammation and a prothrombotic state.

Objective

This rapid systematic review aims to synthesize evidence on thromboembolism incidence and outcomes with antithrombotic therapies in COVID-19.

Data sources

We searched MEDLINE (Ovid), Cochrane Rapid Reviews, PROSPERO, and the WHO COVID-19 Database from January 1, 2003, to April 22, 2020, for studies meeting pre-specified inclusion criteria.

Study selection, data extraction, and synthesis

One investigator identified articles for inclusion, abstracted data, and performed quality assessment, with second reviewer checking.

Results

Incidence of thromboembolism among hospitalized patients with COVID-19 ranged from 25 to 53% in 4

SUBMITTER: Maldonado E 

PROVIDER: S-EPMC7299557 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature