The clinical treatment and outcome of cerebellopontine angle medulloblastoma: a retrospective study of 15 cases.

ABSTRACT: Medulloblastoma (MB) is the most common malignant pediatric brain tumor arising in the cerebellum or the 4^th ventricle. Cerebellopontine angle (CPA) MBs are extremely rare tumors, with few cases previously described. In this study, we sought to describe the clinical characteristics, molecular features and outcomes of CPA MB. We retrospectively reviewed a total of 968 patients who had a histopathological diagnosis of MB at the Beijing Neurosurgical Institute between 2002 and 2016. The demographic characteristics, clinical manifestations and radiological features were retrospectively analyzed. Molecular subgroup was evaluated by the expression profiling array or immunohistochemistry. Overall survival (OS) and progression-free survival (PFS) were calculated using Kaplan-Meier analy

SUBMITTER: Wu T 

PROVIDER: S-EPMC7300107 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature