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Emergence of novel coronavirus and progress toward treatment and vaccine.

ABSTRACT: In late December 2019, a group of patients was observed with pneumonia-like symptoms that were linked with a wet market in Wuhan, China. The patients were found to have a novel coronavirus genetically related to a bat coronavirus that was termed SARS-CoV-2. The virus gradually spread worldwide and was declared a pandemic by WHO. Scientists have started trials on potential preventive and treatment options. Currently, there is no specific approved treatment for SARS-CoV-2, and various clinical trials are underway to explore better treatments. Some previously approved antiviral and other drugs have shown some in vitro activity. Here we summarize the fight against this novel coronavirus with particular focus on the different treatment options and clinical trials exploring treatment as well as work done toward development of vaccines.

SUBMITTER: Khan MM

PROVIDER: S-EPMC7300813 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Emergence of novel coronavirus and progress toward treatment and vaccine.

Khan Muhammad Muzamil MM Noor Amna A Madni Asadullah A Shafiq Mudassir M

Reviews in medical virology 20200604 4

In late December 2019, a group of patients was observed with pneumonia-like symptoms that were linked with a wet market in Wuhan, China. The patients were found to have a novel coronavirus genetically related to a bat coronavirus that was termed SARS-CoV-2. The virus gradually spread worldwide and was declared a pandemic by WHO. Scientists have started trials on potential preventive and treatment options. Currently, there is no specific approved treatment for SARS-CoV-2, and various clinical tri ...[more]

PMID: 32495979

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