COVID-19 in Parkinson's Disease Patients Living in Lombardy, Italy.
Ontology highlight
ABSTRACT: Background
It is unknown whether patients with PD are at greater risk of COVID-19, what their risk factors are, and whether their clinical manifestations differ from the general population.Objectives
The study aimed to address all these issues.Methods
In a case-controlled survey, we interviewed 1,486 PD patients attending a single tertiary center in Lombardy, Italy and 1,207 family members (controls).Results
One hundred five (7.1%) and 92 controls (7.6%) were identified as COVID-19 cases. COVID-19 patients were younger, more likely to suffer from chronic obstructive pulmonary disease, to be obese, and vitamin D nonsupplemented than unaffected patients. Six patients (5.7%) and 7 family members (7.6%) died from COVID-19. Patients were less likely to report shortness of breath and require hospitalization.Conclusions
In an unselected large cohort of nonadvanced PD patients, COVID-19 risk and mortality did not differ from the general population, but symptoms appeared to be milder. The possible protective role of vitamin D supplementation warrants future studies. © 2020 International Parkinson and Movement Disorder Society.
SUBMITTER: Fasano A
PROVIDER: S-EPMC7300944 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
COVID-19 in Parkinson's Disease Patients Living in Lombardy, Italy.
Fasano Alfonso A Cereda Emanuele E Barichella Michela M Cassani Erica E Ferri Valentina V Zecchinelli Anna Lena AL Pezzoli Gianni G
Movement disorders : official journal of the Movement Disorder Society 20200626 7
<h4>Background</h4>It is unknown whether patients with PD are at greater risk of COVID-19, what their risk factors are, and whether their clinical manifestations differ from the general population.<h4>Objectives</h4>The study aimed to address all these issues.<h4>Methods</h4>In a case-controlled survey, we interviewed 1,486 PD patients attending a single tertiary center in Lombardy, Italy and 1,207 family members (controls).<h4>Results</h4>One hundred five (7.1%) and 92 controls (7.6%) were iden ...[more]
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