Treatment Withdrawal Following Remission in Juvenile Idiopathic Arthritis: A Systematic Review of the Literature.

ABSTRACT:

Background

Early diagnosis and treatment of juvenile idiopathic arthritis (JIA) with conventional and biologic disease-modifying anti-rheumatic drugs have vastly improved outcomes for children with these diseases. Currently, a large proportion of children with JIA are able to achieve clinical inactive disease and remission. With this success, important questions have arisen about when medications can be stopped and how to balance the risks and benefits of continuing medications versus the potential for flare after stopping.

Aim

The aim was to conduct a systematic review of the available literature to summarize current evidence about medication withdrawal for JIA in remission.

Methods

We conducted a systematic literature search in PubMed and Embase from 1990 to 2019. R

SUBMITTER: Halyabar O 

PROVIDER: S-EPMC7301222 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature