Association of Azithromycin Use With Cardiovascular Mortality.

ABSTRACT:

Importance

Azithromycin is one of the most commonly prescribed antibiotics in the US. It has been associated with an increased risk of cardiovascular death in some observational studies.

Objective

To estimate the relative and absolute risks of cardiovascular and sudden cardiac death after an outpatient azithromycin prescription compared with amoxicillin, an antibiotic not known to increase cardiovascular events.

Design, setting, and participants

This retrospective cohort study included 2 large, diverse, community-based integrated care delivery systems with comprehensive capture of encounters and prescriptions from January 1, 1998, to December 31, 2014. The cohort included patients aged 30 to 74 years who had at least 12 months of health-plan enrollment prior to antibi

SUBMITTER: Zaroff JG 

PROVIDER: S-EPMC7301226 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature