Ultrafast flavin/tryptophan radical pair kinetics in a magnetically sensitive artificial protein.

ABSTRACT: Radical pair formation and decay are implicated in a wide range of biological processes including avian magnetoreception. However, studying such biological radical pairs is complicated by both the complexity and relative fragility of natural systems. To resolve open questions about how natural flavin-amino acid radical pair systems are engineered, and to create new systems with novel properties, we developed a stable and highly adaptable de novo artificial protein system. These protein maquettes are designed with intentional simplicity and transparency to tolerate aggressive manipulations that are impractical or impossible in natural proteins. Here we characterize the ultrafast dynamics of a series of maquettes with differing electron-transfer distance between a covalently ligated flavin a

SUBMITTER: Bialas C 

PROVIDER: S-EPMC7301759 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature