The effect of age on survival after endoscopic resection versus surgery for T1a esophageal cancer.

ABSTRACT:

Background

Endoscopic resection has emerged as a treatment option for T1a esophageal cancer, but the impact of age on patient selection for surgery versus endoscopic resection has not been well studied. We hypothesized that endoscopic resection would be associated with improved survival compared with surgery in older patients with early esophageal cancer and worse survival in younger patients.

Methods

The National Cancer Database was used to identify patients with cT1aN0M0 esophageal cancer (2010-2015) treated with endoscopic resection or esophagectomy. The relationship between age and treatment effect on survival was modeled with an interaction term in a Cox proportional hazards regression. The primary outcome was overall survival.

Results

A total of 831 patients met

SUBMITTER: Raman V 

PROVIDER: S-EPMC7302422 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature