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Toward Task Connectomics: Examining Whole-Brain Task Modulated Connectivity in Different Task Domains.


ABSTRACT: Human brain anatomical and resting-state functional connectivity have been comprehensively portrayed using MRI, which are termed anatomical and functional connectomes. A systematic examination of tasks modulated whole brain functional connectivity, which we term as task connectome, is still lacking. We analyzed 6 block-designed and 1 event-related designed functional MRI data, and examined whole-brain task modulated connectivity in various task domains, including emotion, reward, language, relation, social cognition, working memory, and inhibition. By using psychophysiological interaction between pairs of regions from the whole brain, we identified statistically significant task modulated connectivity in 4 tasks between their experimental and respective control conditions. Task modulated c

SUBMITTER: Di X 

PROVIDER: S-EPMC7302740 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature