Timing of phase-amplitude coupling is essential for neuronal and functional maturation of audiovisual integration in adolescents.

ABSTRACT:

Objective

The ability to integrate audiovisual information matures late in adolescents, but its neuronal mechanism is still unknown. Recent studies showed that phase-amplitude coupling (PAC) of neuronal oscillations, which is defined as the modulation of high-frequency amplitude by low-frequency phase, is associated with audiovisual integration in adults. Thus, we investigated how PAC develops in adolescents and whether it is related to the functional maturation of audiovisual integration. In particular, we focused on the timing of PAC (or the coupling phase), which is defined as the low-frequency phase with maximum high-frequency amplitude.

Methods

Using magnetoencephalography (MEG) on 15 adults and 14 adolescents while they performed an audiovisual speech integration task,

SUBMITTER: Ohki T 

PROVIDER: S-EPMC7303405 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature