Elevated suPAR Is an Independent Risk Marker for Incident Kidney Disease in Acute Medical Patients.

ABSTRACT:

Introduction

Identifying patients at high risk of developing kidney disease could lead to early clinical interventions that prevent or slow disease progression. Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory biomarker thought to be involved in the pathogenesis and development of kidney disease. We aimed to determine whether elevated plasma suPAR measured at hospital admission is associated with incident kidney disease in patients presenting to the emergency department.

Materials and methods

This was a retrospective registry-based cohort study performed at the Emergency Department of Copenhagen University Hospital Amager and Hvidovre, Hvidovre, Denmark. Patients were included in the study from November 2013 to March 2017 and followed until June 20

SUBMITTER: Iversen E 

PROVIDER: S-EPMC7303513 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature