Microevolutionary Dynamics of Chicken Genomes under Divergent Selection for Adiposity.

ABSTRACT: Decades of artificial selection have significantly improved performance and efficiency of animal production systems. However, little is known about the microevolution of genomes due to intensive breeding. Using whole-genome sequencing, we document dynamic changes of chicken genomes under divergent selection on adiposity over 19 generations. Directional selection reduced within-line but increased between-line genomic differences. We observed that artificial selection tended to result in recruitment of preexisting variations of genes related to adipose tissue growth. In addition, novel mutations contributed to divergence of phenotypes under selection but contributed significantly less than preexisting genomic variants. Integration of 15 generations genome sequencing, genome-wide association

SUBMITTER: Zhang H 

PROVIDER: S-EPMC7303556 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature