The rise of diversity in metabolic platforms across the Candidate Phyla Radiation.

ABSTRACT:

Background

A unifying feature of the bacterial Candidate Phyla Radiation (CPR) is a limited and highly variable repertoire of biosynthetic capabilities. However, the distribution of metabolic traits across the CPR and the evolutionary processes underlying them are incompletely resolved.

Results

Here, we selected ~ 1000 genomes of CPR bacteria from diverse environments to construct a robust internal phylogeny that was consistent across two unlinked marker sets. Mapping of glycolysis, the pentose phosphate pathway, and pyruvate metabolism onto the tree showed that some components of these pathways are sparsely distributed and that similarity between metabolic platforms is only partially predicted by phylogenetic relationships. To evaluate the extent to which gene loss and late

SUBMITTER: Jaffe AL 

PROVIDER: S-EPMC7304191 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature