The V410L knockdown resistance mutation occurs in island and continental populations of Aedes aegypti in West and Central Africa.

ABSTRACT: The extensive use of insecticides for vector control has led to the development of insecticide resistance in Aedes aegypti populations on a global scale, which has significantly compromised control actions. Insecticide resistance, and its underlying mechanisms, has been investigated in several countries, mostly in South American and Asian countries. In Africa, however, studies reporting insecticide resistance are rare and data on resistance mechanisms, notably knockdown resistance (kdr) mutations, is scarce. In this study, the recently described V410L kdr mutation is reported for the first time in old world Ae. aegypti populations, namely from Angola and Madeira island. Two additional kdr mutations, V1016I and F1534C, are also reported for the first time in populations from Angola and Cape

SUBMITTER: Ayres CFJ 

PROVIDER: S-EPMC7304628 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature