Change in neural response during emotion regulation is associated with symptom reduction in cognitive behavioral therapy for anxiety disorders.

ABSTRACT:

Background

Anxiety disorders are debilitating conditions that can be treated with cognitive behavioral therapy (CBT). Increased understanding of the neurobiological correlates of CBT may inform treatment improvements and personalization. Prior neuroimaging studies point to treatment-related changes in anterior cingulate, insula, and other prefrontal regions during emotional processing, yet to date the impact of CBT on neural substrates of "top down" emotion regulation remains understudied. We examined the relationship between symptom changes assessed over the course of CBT treatment sessions and pre- to post-treatment neural change during an emotion regulation task.

Method

In the current study, a sample of 30 participants with panic disorder or generalized anxiety disorder c

SUBMITTER: Bomyea J 

PROVIDER: S-EPMC7304745 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature