Lytic potential of Lysobacter capsici VKM B-2533^T: bacteriolytic enzymes and outer membrane vesicles.

ABSTRACT: Recent recurrent outbreaks of bacterial resistance to antibiotics have shown the critical need to identify new lytic agents to combat them. The species Lysobacter capsici VKM B-2533^T possesses a potent antimicrobial action against a number of bacteria, fungi and yeasts. Its activity can be due to the impact of bacteriolytic enzymes, antibiotics and peptides. This work isolated four homogeneous bacteriolytic enzymes and a mixture of two proteins, which also had a bacteriolytic activity. The isolates included proteins identical to L. enzymogenes α- and β-lytic proteases and lysine-specific protease. The proteases of 26 kDa and 29 kDa and a protein identified as N-acetylglycosaminidase had not been isolated in Lysobacter earlier. The isolated β-lytic protease digested live methicil

SUBMITTER: Afoshin AS 

PROVIDER: S-EPMC7305183 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature