Modelling integrated antiretroviral treatment and harm reduction services on HIV and overdose among people who inject drugs in Tijuana, Mexico.

ABSTRACT:

Introduction

The HIV epidemic in Tijuana, Mexico is concentrated in key populations, including people who inject drugs (PWID). However, HIV interventions among PWID are minimal, and federal funding was provided for compulsory abstinence programmes associated with HIV and overdose. Alternatively, opioid agonist therapy reduces overdose, reincarceration, HIV, while improving antiretroviral therapy (ART) outcomes. We assessed potential impact and synergies of scaled-up integrated ART and opioid agonist therapy, compared to scale-up of each separately, and potential harms of compulsory abstinence programmes on HIV and fatal overdose among PWID in Tijuana.

Methods

We developed a dynamic model of HIV transmission and overdose among PWID in Tijuana. We simulated scale-up of opioid

SUBMITTER: Cepeda JA 

PROVIDER: S-EPMC7305416 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature