Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19.

ABSTRACT:

Introduction

Management of the COVID-19 pandemic is hampered by long delays associated with centralised laboratory PCR testing. In hospitals this leads to poor patient flow and nosocomial transmission and so rapid, accurate diagnostic tests are urgently required. The FebriDx is a point-of-care test that detects an antiviral host response protein in finger prick blood within 10 min, but its accuracy for the identification of COVID-19 is unknown.

Methods

We performed a real-world diagnostic accuracy study of FebriDx in hospitalised patients during the first wave of the pandemic. Measures of diagnostic accuracy were calculated based on FebriDx results compared to the reference standard of SARS-CoV-2 PCR on combined nose and throat swabs. A multivariable predictive model includi

SUBMITTER: Clark TW 

PROVIDER: S-EPMC7306108 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature