Molecular Detection of Carbapenemase-Encoding Genes in Multidrug-Resistant Acinetobacter baumannii Clinical Isolates in South Africa.

ABSTRACT:

Introduction

Carbapenem-resistant Acinetobacter baumannii has been responsible for an increasing number of hospital-acquired infections globally. The study investigated the prevalence of carbapenemase-encoding genes in clinical multidrug-resistant A. baumannii strains.

Materials and methods

A total of 100 nonduplicate multidrug-resistant A. baumannii strains were cultured from clinical samples obtained from healthcare facilities in the O. R. Tambo district. The strains were confirmed by detecting the intrinsic bla _OXA-51-like gene. Antimicrobial susceptibility testing was performed by VITEK^® 2 and autoSCAN-4 systems. The MIC of imipenem and meropenem was rechecked by E-test. Colistin MIC was confirmed by the broth microdiluti

SUBMITTER: Anane YA 

PROVIDER: S-EPMC7306865 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature