Clinical outcomes according to cannula configurations in patients with acute respiratory distress syndrome under veno-venous extracorporeal membrane oxygenation: a Korean multicenter study.

ABSTRACT:

Background

Recirculation during veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a known drawback that limits sufficient oxygenation. This study aimed to compare the short-term oxygenation and long-term mortality based on cannula configuration in patients with acute respiratory distress syndrome (ARDS) who receive VV-ECMO, especially in the absence of newly developed dual-lumen, single cannula.

Methods

Data of patients with severe ARDS who received VV-ECMO from 2012 to 2015 at six hospitals were retrospectively analyzed. Primary outcomes were the partial pressure of oxygen (PaO₂) at 1, 4, and 12 h after ECMO initiation and 180-day mortality.

Results

Patients (n = 335) were divided into two groups based on the return cannula site: femoral vein (n

SUBMITTER: Lim SY 

PROVIDER: S-EPMC7306930 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature