Effect of Maintenance Intravenous Iron Treatment on Erythropoietin Dose in Chronic Hemodialysis Patients: A Multicenter Randomized Controlled Trial.

ABSTRACT:

Background

There is no consensus on intravenous (IV) iron supplement dose, schedule, and serum ferritin target in functional iron deficiency anemia to maintain optimum target levels of iron stores by several guidelines.

Objective

To examine the effect of IV iron supplementation to different targets of serum ferritin on erythropoietin dose and inflammatory markers in chronic hemodialysis (HD) patients with functional iron deficiency anemia.

Design

A multicenter, randomized, open-label study.

Setting

In a developing country, Thailand.

Patients

Chronic HD patients with functional iron deficiency anemia.

Measurements

Erythropoietin resistance index, high-sensitivity C-reactive protein, and fibroblast growth factor 23.

Methods

Two hundred adult

SUBMITTER: Susantitaphong P 

PROVIDER: S-EPMC7307402 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature