Obesity and Insulin Resistance, Not Polycystic Ovary Syndrome, Are Independent Predictors of Bone Mineral Density in Adolescents and Young Women.

ABSTRACT:

Introduction

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders that affects females of reproductive age. The characteristic features of PCOS individually have opposing effects on bone mineral density (BMD); however, their cumulative effect on BMD has not been clearly defined. Adolescence and young adulthood span a crucial period in achieving peak bone mass. Thus, a better understanding of the impact of PCOS on BMD in this age group is needed.

Objectives

To determine whether BMD is different between young females with PCOS and controls and to identify factors that influence BMD in this population.

Methods

Data from four cross-sectional studies with a total of 170 females aged 12-25 years with PCOS (n = 123) and controls (n = 47) with a wide

SUBMITTER: Pereira-Eshraghi CF 

PROVIDER: S-EPMC7308184 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature