The Effect of Maternal Multiple Micronutrient Supplementation on Female Early Infant Mortality Is Fully Mediated by Increased Gestation Duration and Intrauterine Growth.

ABSTRACT:

Background

Maternal micronutrient supplementation in pregnancy (MMS) has been shown to improve birth weight among infants in low- and middle-income countries. Recent evidence suggests that the survival benefits of MMS are greater for female infants compared to male infants, but the mechanisms leading to differential effects remain unclear.

Objective

The objective of this study was to examine the potential mechanisms through which MMS acts on infant mortality among Tanzanian infants.

Methods

We used data collected from pregnant women and newborns in a randomized, double-blind, placebo-controlled trial of MMS conducted in Tanzania to examine mediators of the effect of MMS on 6-wk infant mortality (NCT00197548). Causal mediation analyses with the counterfactual approach

SUBMITTER: Quinn MK 

PROVIDER: S-EPMC7308623 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature