Cardiovascular, carcinogenic and reproductive effects of nicotine exposure: A narrative review of the scientific literature.

ABSTRACT: The emergence of new tobacco heating products and electronic nicotine delivery systems (ENDS) is changing the way humans are exposed to nicotine. The purpose of this narrative review is to provide a broad overview of published scientific literature with respect to the effects of nicotine on three key health-related areas: 1) cardiovascular risk, 2) carcinogenesis and 3) reproductive outcomes. These areas are known to be particularly vulnerable to the effects of cigarette smoke, and in addition, nicotine has been hypothesized to play a role in disease pathogenesis. Acute toxicity will also be discussed. The literature to February 2019 suggests that there is no increased cardiovascular risk of nicotine exposure in consumers who have no underlying cardiovascular pathology. There is scientific

SUBMITTER: Price LR 

PROVIDER: S-EPMC7308884 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature