Analyses of spike protein from first deposited sequences of SARS-CoV2 from West Bengal, India.

ABSTRACT: India has recently started sequencing SARS-CoV2 genome from clinical isolates. Currently only few sequences are available from three states in India. Kerala was the first state to deposit complete sequence from two isolates followed by one from Gujarat. On April 27, 2020, the first five sequences from the state of West Bengal (Eastern India) were deposited on GISAID, a global initiative for sharing avian flu data. In this study, we have analysed the spike protein sequences from all five isolates and also compared their similarities or differences with other sequences reported in India and with isolates of Wuhan origin. We report one unique mutation at position 723 and another at 1124 in the S2 domain of spike protein of the isolates from West Bengal only.  There was one mutation downstream

SUBMITTER: Begum F 

PROVIDER: S-EPMC7309413 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature