Early prediction of high flow nasal cannula therapy outcomes using a modified ROX index incorporating heart rate.

ABSTRACT:

Background

The ROX index (ratio of pulse oximetry/FIO₂ to respiratory rate) has been validated to predict high flow nasal cannula therapy (HFNC) outcomes in patients with pneumonia. We evaluated a modified ROX index incorporating heart rate (HR) in patients initiated on HFNC for acute hypoxemic respiratory failure and as a preventative treatment following planned extubation.

Methods

We performed a prospective observational cohort study of 145 patients treated with HFNC. ROX-HR index was defined as the ratio of ROX index over HR (beats/min), multiplied by a factor of 100. Evaluation was performed using area under the receiving operating characteristic curve (AUROC) and cutoffs assessed for prediction of HFNC failure: defined as the need for mechanical ventilation.<

SUBMITTER: Goh KJ 

PROVIDER: S-EPMC7310118 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature