Asymptomatic and presymptomatic transmission of SARS-CoV-2: A systematic review.

ABSTRACT: Background and Purpose Many of the statutes comprising the shelter-in-place and phased-reopening orders are centered around minimizing asymptomatic and presymptomatic transmission. Assumptions about the presence and relative importance of asymptomatic and presymptomatic transmission are based on case reports, the failing of quarantine measures aimed at sequestering ill patients, viral dynamic studies suggesting SARS-CoV-2 production peaks before symptoms appear, and modeling evidence that calculates serial interval between successive generations of infection. In aggregate, these data offer compelling evidence of asymptomatic and presymptomatic transmission, but individually these studies have notable shortcomings that undermine their conclusions. The purpose of this review is to discuss th

SUBMITTER: Savvides C 

PROVIDER: S-EPMC7310638 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature