Longitudinal Macular Structure-Function Relationships in Glaucoma.

ABSTRACT:

Purpose

To investigate the relationship between longitudinal changes in macular thickness measurements from OCT and changes in central visual field (VF) in patients with glaucoma with central or advanced damage at baseline.

Design

Longitudinal cohort study.

Participants

A total of 116 eyes with ≥3 years of follow-up and ≥5 macular OCT images and central 10° VF tests were selected.

Methods

OCT superpixels and VF locations were matched correcting for retinal ganglion cell (RGC) displacement. Superpixel thickness and VF total deviation (TD) values, in both logarithmic and linear scales, were averaged within 3 eccentricities (3.4°, 5.6°, and 6.8°) and superior and inferior hemiretinas and hemifields. We estimated pointwise TD rates of change and rates of change at

SUBMITTER: Mohammadzadeh V 

PROVIDER: S-EPMC7311272 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature