Coronary Event Analysis in Breast Cancer Patients Who Received Breast-Conserving Surgery and Post-Operative Radiotherapy: a Korean Nationwide Cohort Study.

ABSTRACT:

Purpose

Adjuvant breast radiotherapy (RT) following breast-conserving surgery (BCS) has been reported to induce cardiac toxicity in breast cancer patients. We investigated the incidence and risk factors of major coronary events after breast RT using Korean nationwide Health Insurance Review and Assessment data.

Methods

Using data from a nationwide quality assessment of breast cancer treatment, we identified 3,251 patients who received breast RT after BCS in 2013. Data about major coronary events were additionally collected from national claims data. We defined major coronary events according to the International Classification of Diseases, 10th revision (ICD-10) codes I20-25.

Results

A total of 172 major coronary events (5.3%) occurred among 3,251 breast cancer patien

SUBMITTER: Sung SY 

PROVIDER: S-EPMC7311360 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature