Identification and Expression Profiling of Toll-Like Receptors of Brown Trout (<i>Salmo trutta</i>) during Proliferative Kidney Disease.

ABSTRACT: Proliferative kidney disease is an emerging disease among salmonids in Europe and North America caused by the myxozoan parasite Tetracapsuloides bryosalmonae. The decline of endemic brown trout (Salmo trutta) in the Alpine streams of Europe is fostered by T. bryosalmonae infection. Toll-like receptors (TLRs) are a family of pattern recognition receptors that acts as sentinels of the immune system against the invading pathogens. However, little is known about the TLRs' response in salmonids against the myxozoan infection. In the present study, we identified and evaluated TLR1, TLR19, and TLR13-like genes of brown trout using data-mining and phylogenetic analysis. The expression pattern of TLRs was examined in the posterior kidney of brown trout infected with T. bryos

SUBMITTER: Sudhagar A 

PROVIDER: S-EPMC7312180 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature