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Assessment of Breast Cancer Mortality Trends Associated With Mammographic Screening and Adjuvant Therapy From 1986 to 2013 in the State of Victoria, Australia.


ABSTRACT:

Importance

Diagnosis of early breast cancer (EBC) in women by mammographic screening and postsurgical adjuvant endocrine therapy and chemotherapy (termed adjuvant therapy) began simultaneously in many countries in the 1990s. Subsequent breast cancer mortality declines were variously attributed to mammographic screening and/or adjuvant therapy.

Objective

To determine the relative mortality reductions associated with these 2 interventions in women with EBC who had been exposed to both.

Design, setting, and participants

This secondary analysis of cross-sectional studies assessed groups of women with invasive breast cancer in the State of Victoria, Australia, from January 1, 1982, to December 31, 2013, who were included in the Victorian Cancer Registry (VCR). The populati

SUBMITTER: Burton R 

PROVIDER: S-EPMC7312387 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature