Occupational Lead Exposure and Brain Tumors: Systematic Review and Meta-Analysis.

ABSTRACT: (1) Background: Due to inconsistencies in epidemiological findings, there has been uncertainty regarding the association of lead compounds with brain tumors. We performed a meta-analysis of published case-control and cohort studies exploring lead compound exposure and brain tumor risk. (2) Methods: We searched PubMed, Embase^®, and Cochrane to find eligible studies. Eighteen studies were selected for assessment of occupational exposure to lead compound and brain tumor. Pooled estimates of odds ratios (ORs) were obtained using random effects models. We assessed the differences through subgroup analysis according to tumor type, study design, measurements of exposure, and tumor outcome. Statistical tests for publication bias, heterogeneity, and sensitivity analysis wer

SUBMITTER: Ahn J 

PROVIDER: S-EPMC7312535 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature