Healthspan Enhancement by Olive Polyphenols in C. elegans Wild Type and Parkinson's Models.

ABSTRACT: Parkinson's disease (PD) is the second most prevalent late-age onset neurodegenerative disorder, affecting 1% of the population after the age of about 60 years old and 4% of those over 80 years old, causing motor impairments and cognitive dysfunction. Increasing evidence indicates that Mediterranean diet (MD) exerts beneficial effects in maintaining health, especially during ageing and by the prevention of neurodegenerative disorders. In this regard, olive oil and its biophenolic constituents like hydroxytyrosol (HT) have received growing attention in the past years. Thus, in the current study we test the health-promoting effects of two hydroxytyrosol preparations, pure HT and Hidrox® (HD), which is hydroxytyrosol in its "natural" environment, in the established invertebrate model organism

SUBMITTER: Di Rosa G 

PROVIDER: S-EPMC7312680 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature