Oral Microbiome of Children Living in an Isolated Area in Myanmar.

ABSTRACT: Several studies have shown that the oral microbiome is related to systemic health, and a co-relation with several specific diseases has been suggested. The oral microbiome depends on environmental- and community-level factors. In this observational study, the oral microbiomes of children of isolated mountain people were analyzed with respect to the core oral microbiome and etiology of dental caries. We collected samples of supragingival plaque from children (age 9-13) living in the Chin state of Myanmar. After DNA extraction and purification, next-generation sequencing of the V3-V4 hypervariable regions of the 16S rRNA was conducted. From thirteen subjects, 263,458 valid reads and 640 operational taxonomic units were generated at a 97% identity cut-off value. At the phylum level, Proteobac

SUBMITTER: Nomura Y 

PROVIDER: S-EPMC7312721 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature