Disruption of Circadian Rhythms: A Crucial Factor in the Etiology of Infertility.

ABSTRACT: : Infertility represents a growing health problem in industrialized countries. Thus, a greater understanding of the molecular networks involved in this disease could be critical for the development of new therapies. A recent finding revealed that circadian rhythmicity disruption is one of the main causes of poor reproductive outcome. The circadian clock system beats circadian rhythms and modulates several physiological functions such as the sleep-wake cycle, body temperature, heart rate, and hormones secretion, all of which enable the body to function in response to a 24 h cycle. This intricated machinery is driven by specific genes, called "clock genes" that fine-tune body homeostasis. Stress of modern lifestyle can determine changes in hormone secretion, favoring the onset of infertility

SUBMITTER: Sciarra F 

PROVIDER: S-EPMC7312974 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature