Excess free fructose, apple juice, high fructose corn syrup and childhood asthma risk - the National Children's Study.

ABSTRACT:

Background

Recent research provides consistent evidence that the unexplained doubling of childhood asthma prevalence (1980-1995), its continued climb and 2013 plateau, may be associated with the proliferation of high-fructose-corn-syrup (HFCS) in the US food supply. The HFCS used in soft drinks has been shown to contain a higher fructose-to-glucose ratio than previously thought. This coincides with a preference shift from orange to apple juice among young children. Apple juice naturally contains a high (≥2:1) fructose-to-glucose ratio. Thus, children have received high excess-free-fructose doses, the fructose type associated with fructose malabsorption. Unabsorbed excess-free-fructose in the gut may react with dietary proteins to form immunogens that bind asthma mediating receptors

SUBMITTER: DeChristopher LR 

PROVIDER: S-EPMC7313206 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature