Ontology highlight
ABSTRACT:
SUBMITTER: Liu SJ
PROVIDER: S-EPMC7313374 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Cell reports 20200201 5
Ependymomas exist within distinct genetic subgroups, but the molecular diversity within individual ependymomas is unknown. We perform multiplatform molecular profiling of 6 spatially distinct samples from an ependymoma with C11orf95-RELA fusion. DNA methylation and RNA sequencing distinguish clusters of samples according to neuronal development gene expression programs that could also be delineated by differences in magnetic resonance blood perfusion. Exome sequencing and phylogenetic analysis r ...[more]