Association of hypertension and antihypertensive treatment with COVID-19 mortality: a retrospective observational study.

ABSTRACT:

Aims

It remains unknown whether the treatment of hypertension influences the mortality of patients diagnosed with coronavirus disease 2019 (COVID-19).

Methods and results

This is a retrospective observational study of all patients admitted with COVID-19 to Huo Shen Shan Hospital. The hospital was dedicated solely to the treatment of COVID-19 in Wuhan, China. Hypertension and the treatments were stratified according to the medical history or medications administrated prior to the infection. Among 2877 hospitalized patients, 29.5% (850/2877) had a history of hypertension. After adjustment for confounders, patients with hypertension had a two-fold increase in the relative risk of mortality as compared with patients without hypertension [4.0% vs. 1.1%, adjusted hazard ratio (HR)

SUBMITTER: Gao C 

PROVIDER: S-EPMC7314067 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature