Association between renin-angiotensin system inhibitors and COVID-19 complications.

ABSTRACT:

Aims

To describe the characteristics of patients hospitalized with COVID-19 (including their long-term at-home medication use), and compare them with regard to the course of the disease. To assess the association between renin-angiotensin system inhibitors (RASIs) and disease progression and critical outcomes.

Methods and results

All consecutive hospitalized patients with laboratory-confirmed COVID-19 in a university hospital in Amiens (France) were included in this study. The primary composite endpoint was admission to an intensive care unit (ICU) or death before ICU admission. Univariable and multivariable logistic regression models were used to identify factors associated with the composite endpoint. Between 28 February 2020 and 30 March 2020, a total of 499 local patient

SUBMITTER: Liabeuf S 

PROVIDER: S-EPMC7314068 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature