Convalescent plasma transfusion a promising therapy for coronavirus diseases 2019 (COVID-19): current updates.

ABSTRACT: While there is no proven treatment available for coronavirus disease 2019 (COVID-19), convalescent plasma (CP) may provide therapeutic relief as the number of cases escalate steeply world-wide. At the time of writing this review, vaccines, monoclonal antibodies or drugs are still lacking for the recent large COVID-19 outbreak, which restores the interest in CP as an empirical life-saving treatment. However, formal proof of efficacy is needed. The purpose of this review is to summarize all historical clinical trials on COVID-19 infected patients treated with CP to provide precise evidence for the efficacy and effectiveness of CP therapy in severe COVID-19 patients. Although there are many clinical trials in progress, high-quality clinical evidence is still lacking to analyze the existing pr

SUBMITTER: Verma HK 

PROVIDER: S-EPMC7314270 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature