Long-Term Cognitive Impairment Associated With Delirium in Acute Neurological Injury.

ABSTRACT:

Objectives

To characterize the risk of long-term cognitive impairment associated with delirium in acute neurologic injury patients.

Design

We analyzed a 10-year cohort of adult acute neurologic injury patients (stroke and traumatic brain injury) without preexisting mild cognitive impairment or dementia, utilizing administrative databases. Patients were followed for in-hospital delirium and mild cognitive impairment or dementia. We report incidence and adjusted hazard ratios for mild cognitive impairment or dementia associated with delirium. Subgroups analyzed include acute neurologic injury categories, dementia subtypes, repeated delirium exposure, and age strata.

Setting

We used state emergency department and state inpatient databases for New York, Florida, and Calif

SUBMITTER: Meeks JR 

PROVIDER: S-EPMC7314325 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature