Slow oscillation-spindle coupling predicts enhanced memory formation from childhood to adolescence.

ABSTRACT: Precise temporal coordination of slow oscillations (SO) and sleep spindles is a fundamental mechanism of sleep-dependent memory consolidation. SO and spindle morphology changes considerably throughout development. Critically, it remains unknown how the precise temporal coordination of these two sleep oscillations develops during brain maturation and whether their synchronization indexes the development of memory networks. Here, we use a longitudinal study design spanning from childhood to adolescence, where participants underwent polysomnography and performed a declarative word-pair learning task. Performance on the memory task was better during adolescence. After disentangling oscillatory components from 1/f activity, we found frequency shifts within SO and spindle frequency bands. Conseq

SUBMITTER: Hahn MA 

PROVIDER: S-EPMC7314542 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature