Ontology highlight
ABSTRACT:
SUBMITTER: Lee RA
PROVIDER: S-EPMC7315020 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Lee Rose A RA Al Dhaheri Fatima F Pollock Nira R NR Sharma Tanvi S TS
Journal of clinical microbiology 20200624 7
Metagenomic next-generation sequencing (mNGS) of plasma cell-free DNA (cfDNA) is commercially available, but its role in the workup of infectious diseases is unclear. To understand the clinical utility of plasma mNGS, we retrospectively reviewed patients tested at a pediatric institution over 2 years to evaluate the clinical relevance of the organism(s) identified and the impact on antimicrobial management. We also investigated the effect of pretest antimicrobials and interpretation of molecules ...[more]