Structure and Evolution of Acinetobacter baumannii Plasmids.

ABSTRACT: Acinetobacter baumannii is an emergent bacterial pathogen that provokes many types of infections in hospitals around the world. The genome of this organism consists of a chromosome and plasmids. These plasmids vary over a wide size range and many of them have been linked to the acquisition of antibiotic-resistance genes. Our bioinformatic analyses indicate that A. baumannii plasmids belong to a small number of plasmid lineages. The general structure of these lineages seems to be very stable and consists not only of genes involved in plasmid maintenance functions but of gene sets encoding poorly characterized proteins, not obviously linked to survival in the hospital setting, and opening the possibility that they improve the parasitic properties of plasmids. An analysis of gen

SUBMITTER: Salgado-Camargo AD 

PROVIDER: S-EPMC7315799 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature