Risk factors for pleural effusion recurrence in patients with malignancy.

ABSTRACT:

Background and objective

The main purpose of treatment in patients with malignant pleural effusion (MPE) is symptom palliation. Currently, patients undergo repeat thoracenteses prior to receiving a definitive procedure as clinicians are not aware of the risk factors associated with fluid recurrence. The primary objective of this study was to identify risk factors associated with recurrent symptomatic MPE.

Methods

Retrospective multicentre cohort study of patients who underwent first thoracentesis was performed. The primary outcome was time to fluid recurrence requiring intervention in patients with evidence of metastatic disease. We used a cause-specific hazard model to identify risk factors associated with fluid recurrence. We also developed a predictive model, utilizing Fi

SUBMITTER: Grosu HB 

PROVIDER: S-EPMC7315912 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature