Real-time co-localized OCT surveillance of laser therapy using motion corrected speckle decorrelation.

ABSTRACT: We present a system capable of real-time delivery and monitoring of laser therapy by imaging with optical coherence tomography (OCT) through a double-clad fiber (DCF). A double-clad fiber coupler is used to inject and collect OCT light into the core of a DCF and inject the therapy light into its larger inner cladding, allowing for both imaging and therapy to be perfectly coregistered. Monitoring of treatment depth is achieved by calculating the speckle intensity decorrelation occurring during tissue coagulation. Furthermore, an analytical noise correction was used on the correlation to extend the maximum monitoring depth. We also present a method for correcting motion-induced decorrelation using a lookup table. Using the value of the noise- and motion-corrected correlation coefficient in a

SUBMITTER: Maltais-Tariant R 

PROVIDER: S-EPMC7316020 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature