Effect of antithrombotic stewardship on the efficacy and safety of antithrombotic therapy during and after hospitalization.

ABSTRACT:

Background

Although the benefits of antithrombotic drugs are indisputable to reduce thrombotic events, they carry a high risk of compromising patient safety. No previous studies investigated the implementation and (cost-) effectiveness of a hospital-based multidisciplinary antithrombotic team on bleeding and thrombotic outcomes. The primary aim of this study was to compare the proportion of patients with a composite end point consisting of one or more bleeding episodes or one or more thrombotic event from hospitalization until three months after hospitalization.

Methods and findings

A prospective, multicenter before-after intervention study was conducted in two Dutch hospitals. Adult patients hospitalized between October 2015 and December 2017 treated with anticoagulant ther

SUBMITTER: Dreijer AR 

PROVIDER: S-EPMC7316339 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature