Adverse childhood experiences are associated with increased risk of miscarriage in a national population-based cohort study in England.

ABSTRACT:

Study question

Is there an association between adverse childhood experiences (ACE) and the risk of miscarriage in the general population?

Summary answer

Specific ACE as well as the summary ACE score were associated with an increased risk of single and recurrent miscarriages.

What is known already

There is scarce evidence on the association between ACE and miscarriage risk.

Study design, size, duration

We conducted a retrospective national cohort study. The sample consisted of 2795 women aged 55-89 years from the English Longitudinal Study of Ageing (ELSA).

Participants/materials, setting, methods

Our study was population-based and included women who participated in the ELSA Life History Interview in 2007. We estimated multinomial logistic regression mode

SUBMITTER: Demakakos P 

PROVIDER: S-EPMC7316498 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature