A flexible and physically transient electrochemical sensor for real-time wireless nitric oxide monitoring.

ABSTRACT: Real-time sensing of nitric oxide (NO) in physiological environments is critically important in monitoring neurotransmission, inflammatory responses, cardiovascular systems, etc. Conventional approaches for NO detection relying on indirect colorimetric measurement or built with rigid and permanent materials cannot provide continuous monitoring and/or require additional surgical retrieval of the implants, which comes with increased risks and hospital cost. Herein, we report a flexible, biologically degradable and wirelessly operated electrochemical sensor for real-time NO detection with a low detection limit (3.97 nmol), a wide sensing range (0.01-100 μM), and desirable anti-interference characteristics. The device successfully captures NO evolution in cultured cells and organs, with result

SUBMITTER: Li R 

PROVIDER: S-EPMC7316789 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature