Danhong Injection for the Treatment of Hypertensive Nephropathy: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

Danhong Injection (DHI) has been widely used to treat various diseases in China for many years. The objective of this systematic review was to evaluate the efficacy of DHI combined with antihypertensive drugs for treatment of hypertensive nephropathy.

Methods

Seven databases were searched from inception to September 21st, 2019. Randomized controlled trials comparing DHI combined with antihypertensive drugs versus antihypertensive drugs alone were extracted. The primary outcome was microalbuminuria (mALB). Secondary outcomes included systolic blood pressure (SBP), diastolic blood pressure (DBP), and serum creatinine (SCr).

Results

Fifteen studies were included in the meta-analysis, which indicated that DHI combined with antihypertensive drugs has advan

SUBMITTER: Li Y 

PROVIDER: S-EPMC7316888 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature